User:Faeder

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James R. Faeder, PhD
Associate Professor

Department of Computational Biology
University of Pittsburgh School of Medicine
3082 BST3, 3501 Fifth Avenue, Pittsburgh, PA 15217
(412) 648-8171, office; (412) 337-6190, cell
faeder@pitt.edu

Contents

Research Interests

  • Rule-based modeling of biological networks
  • Signal transduction
  • Theoretical immunology
  • Methods for multi-scale modeling
  • Uncertainty analysis and model refinement

Selected Publications

  • B. Goldstein, J. R. Faeder, and W. S. Hlavacek (2004) Mathematical and computational models of immune-receptor signalling. Nat. Rev. Immunol., 4, 445-456. [1]
  • J. R. Faeder, M. L. Blinov, B. Goldstein and W. S. Hlavacek (2005) Rule-based modeling of biochemical networks. Complexity, 10, 22-41. [2]
  • J. R. Faeder, M. L. Blinov, B. Goldstein, and W. S. Hlavacek (2005) Combinatorial complexity and dynamical restriction of network flows in signal transduction. IEE Syst. Biol., 2, 5-15. [3]
  • M. L. Blinov, J. R. Faeder, B. Goldstein, and W. S. Hlavacek (2006) A Network Model of Early Events in Epidermal Growth Factor Receptor Signaling That Accounts for Combinatorial Complexity. Biosystems, 83, 136-151. [4]
  • M. L. Blinov, J. Yang, J. R. Faeder, and W. S. Hlavacek (2006) Depicting signaling cascades. Nat. Biotechnol., 24, 137-138. [5]
  • W. S. Hlavacek, J. R. Faeder, M. L. Blinov, R. G. Posner, M. Hucka, and W. Fontana (2006) Rules for modeling signal-transduction systems. Sci. STKE., 2006, re6. [6]
  • C. Torigoe, J. R. Faeder, J. M. Oliver, and B. Goldstein (in press) Kinetic Proofreading of Ligand-FcεRI Interactions May Persist beyond LAT Phosphorylation. J. Immunol.. [7]

Recent Presentations

  • A Tutorial for BioNetGen2, presented at the Multi-scale Modeling Short Course, Chemical Engineering Department, University of Delaware. February, 2006 [8]
  • Mathematical and Computational Modeling of Cell Signaling, presented at USAMRIID, Frederick, MD, May, 2006. [9]

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